Genetics and molecular biology

Genetics and Molecular Biology

Pneumoviruses: Molecular Genetics and Reverse Genetics

Pneumoviruses are responsible for significant respiratory disease in their hosts and represent a major problemfor human and animal health. Pneumoviruses are members of the family Paramyxoviridae, subfamilyPneumovirinae and the virus particles consist of a negative-sense, nonsegmented RNA genome within a helical nucleocapsid structure enveloped in a lipid membrane derived from the ho...

Breeding and Genetics: Molecular Biology and Genomics

Preservation of bio-specimens for molecular biological applications traditionally involves freezing which increases laboratory and research project costs. Protection and stabilization of DNA at room temperature (RT) may eliminate the costs associated with freezer storage. However, there is a paucity of information describing the yield, purity, and integrity of DNA stored at RT. Objectives were ...

Statistical Applications in Genetics and Molecular Biology

An important challenge in statistical genomics concerns integrating experimental data with exogenous information about gene function. A number of statistical methods are available to address this challenge, but most do not accommodate complexities in the functional record. To infer activity of a functional category (e.g., a gene ontology term), most methods use gene-level data on that category,...

Molecular biology and genetics of tubulin.

PERSPECTIVES AND SUMMARY .............................................................. 332 HETEROGENEITY OF TUBULIN POLYPEPTIDES: AN HISTORICAL CHRONICAL ............................................................................ 334 COMPLEXITY OF TUBULIN GENE SEQUENCES .......................................... 336 Tubulin Genes in Unicellular Organisms .........................................